The verdict
For most lean B2B founders, Lemlist is the better default. You get every channel in one predictable per-seat price, a 650M+ lead database and lemwarm deliverability built in, and personalisation (image, video and landing-page) that no rival matches, with AI features you can lean on without a usage cap. It is the lower-risk, lower-friction way to run real multichannel outreach solo.
Reply.io earns its place the moment you want the machine to do the prospecting. Its 1B+ contact database is larger, and its AI SDR, Jason, is a true agent that drafts, replies, handles objections and books meetings rather than just suggesting copy. But that capability sits on a pricier tier, and LinkedIn and call steps are charged on top of the base plan, so the all-in cost climbs faster than the headline 49 USD suggests.
Neither tool has a free plan, so trial both on a real campaign before you commit. The decision is not features, it is whether you are buying a sharper outreach cockpit (Lemlist) or an AI SDR that works the list for you (Reply.io).
Side by side
| 10 points compared | ||
|---|---|---|
| Starts at | $55/mo | $49/mo |
| Free plan | No | No |
| API | Yes | Yes |
| MCP server | Yes | Yes |
| AI reply handling | Yes | Yes |
| Built-in email warmup | Yes | Yes |
| Built-in lead database | Yes | Yes |
| Built-in outreach (sequences/dialer) | Yes | Yes |
| LinkedIn automation | Yes | Yes |
| Unified inbox | Yes | Yes |
| Links |
Plans and pricing
Lemlist
- Email$69/mo
- Multichannel$109/mo
Reply.io
- Email Volume$588/yr
- Multichannel$99/mo/seat
- Jason AI SDR$500/mo
Who each is for
Choose Lemlist if…
Pick Lemlist if you are a solo founder or small team running multichannel outreach yourself and you want one predictable bill. You get email, LinkedIn, SMS, WhatsApp and calls bundled into a single per-seat price (from 39 USD/mo, 31 USD annual), so there are no surprise add-on lines as you add channels. Its 650M+ database, email and phone enrichment, and lemwarm deliverability mean you can build the list, warm the inbox and send from one place. And if personalisation is your edge, Lemlist's image, video and landing-page personalisation, plus uncapped AI, is the strongest in the category. Best for the founder who wants a sharp tool they drive, not an agent they supervise.
Choose Reply.io if…
Pick Reply.io if you want AI to carry the prospecting load. Its AI SDR, Jason, is a genuine agent: it drafts sequences, answers buyer queries, handles objections and books meetings largely on its own, which is the right call when your time is worth more on closing than on sending. The built-in database is larger at 1B+ contacts, useful if you are prospecting wide or into thin niches. The trade-off is cost shape: the base email plan starts at 49 USD/user/mo, multichannel is ~89 USD, LinkedIn and call steps are add-ons, and the AI SDR sits on a higher tier. If you have the budget and want a system that runs outbound rather than one you operate by hand, Reply.io is the stronger buy.
Other options worth a look
From $49/moFind B2B prospects and run email and phone outreach campaigns from one unified platform.OutboundFree planAffiliate link
From $85/mo yearlySends high-volume cold email across multiple mailboxes with automated warmup and a unified reply inbox.OutboundAffiliate link
From $32/mo yearlyRun cold email outreach at scale with unlimited mailboxes, warm-up automation and lead verification.Outbound
From $15/moBuilds sender reputation for new email accounts by warming them through a network of real inboxes.Outbound
From €79/mo yearlyIdentifies website visitors by company and provides EU-based B2B contact data with buyer intent signals.OutboundFree planAffiliate link
From €34/mo yearlyFinds and verifies professional email addresses and sends cold email sequences from one workspace.OutboundFree plan